Spanil 10 mg is a prescription medication used to relieve abdominal pain and spasms associated with gastrointestinal and genitourinary conditions. Its active ingredient, Hyoscine Butylbromide, belongs to the antispasmodic drug class, which works by relaxing smooth muscles in the digestive and urinary tracts. Spanil provides rapid relief from cramps, colicky pain, and discomfort, making it suitable for patients experiencing abdominal or pelvic muscle spasms.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Spanil 10 mg is indicated for the symptomatic relief of:

• Abdominal pain due to intestinal colic, spastic constipation, or gastrointestinal cramps

• Irritable bowel syndrome (IBS)

• Renal colic associated with urinary tract stones

• Spasmodic dysmenorrhea (painful menstruation caused by uterine spasms)

• Other conditions with smooth muscle spasms in the gastrointestinal or urinary systems

Pharmacology and Mode of Action

Hyoscine Butylbromide is a muscarinic receptor antagonist. It selectively blocks the action of acetylcholine on smooth muscles, reducing involuntary contractions in the gastrointestinal and urinary tracts. By inhibiting these spasms, Spanil 10 mg helps alleviate pain, discomfort, and bloating. Unlike other anticholinergic drugs, Hyoscine Butylbromide is poorly absorbed from the gastrointestinal tract, limiting systemic effects and minimizing central nervous system side effects.

Dosage and Administration

• Adult dosage: 10–20 mg orally, up to 3–4 times daily, depending on the severity of symptoms

• Tablets should be taken with or without food, swallowed whole with water

• Elderly patients: Use the lowest effective dose, as sensitivity may be increased

• Dosage should be adjusted individually based on response and tolerability

Drug Interactions

• May enhance the effects of other anticholinergic drugs, increasing the risk of dry mouth, blurred vision, or urinary retention

• Concomitant use with antihistamines, tricyclic antidepressants, or other drugs with anticholinergic activity may intensify side effects

• No significant interactions with most common medications have been reported, but caution is advised in patients on multiple therapies

Contraindications

Spanil 10 mg is contraindicated in patients with:

• Known hypersensitivity to Hyoscine Butylbromide or any tablet components

• Glaucoma (especially narrow-angle)

• Myasthenia gravis

• Paralytic ileus or gastrointestinal obstruction

• Severe ulcerative colitis

• Megacolon or other significant bowel disorders

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Spanil 10 mg is generally well tolerated. Some patients may experience:

• Dry mouth

• Mild dizziness or blurred vision

• Constipation or urinary retention

• Rarely, allergic reactions such as rash or itching

Pregnancy and Lactation

• Pregnancy Category B: Safe use during pregnancy has not been fully established; should be used only if clearly necessary

• Lactation: Unknown if excreted in human milk; caution advised when administering to nursing mothers

Precautions and Warnings

• Use with caution in patients with cardiac conditions, elderly, or those with impaired renal or hepatic function

• Avoid driving or operating machinery if experiencing dizziness or blurred vision

• Not recommended for long-term use without medical supervision

Storage Conditions

• Store below 30°C, in a dry place, away from light and moisture

• Keep out of the reach of children.