Ursotab Tablet 150 mg contains Ursodeoxycholic Acid (UDCA), a hydrophilic bile acid used in the management of liver and gallbladder disorders. It helps improve bile flow, reduces toxic bile acid accumulation, and protects liver cells from damage, supporting overall hepatobiliary health.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Indications
Ursotab Tablet is indicated for:
-
Cholesterol gallstones in a functioning gallbladder
-
Primary biliary cholangitis (PBC)
-
Intrahepatic cholestasis and bile flow disorders
-
Fatty liver disease (as supportive therapy)
-
Cholestatic liver conditions
-
Intrahepatic cholestasis of pregnancy (under medical supervision)
Mechanism of Action
Ursodeoxycholic Acid works through multiple hepatoprotective mechanisms:
-
Reduces intestinal absorption and hepatic secretion of cholesterol
-
Promotes dissolution of cholesterol-rich gallstones
-
Replaces toxic bile acids with less toxic forms
-
Enhances bile secretion and flow
-
Protects liver cells from bile acid–induced injury
Dosage and Administration
-
Usual dose is 10–15 mg/kg/day, divided into 2–3 doses or as directed by a physician
-
Tablets should be taken with food or after meals
-
Swallow whole with water
-
Duration of therapy may range from several months to long-term treatment depending on condition
Benefits
-
Helps dissolve cholesterol gallstones without surgery in selected patients
-
Improves liver function and bile flow
-
Reduces liver inflammation and cellular damage
-
Supports management of chronic liver diseases
-
Suitable for long-term hepatobiliary care
Side Effects
Common side effects may include:
-
Diarrhea
-
Abdominal discomfort
-
Nausea
-
Bloating
Rare side effects:
-
Skin rash or itching
-
Transient elevation of liver enzymes
-
Allergic reactions
Precautions and Warnings
-
Not effective for calcified or pigment gallstones
-
Use cautiously in severe liver impairment
-
Regular monitoring of liver function is recommended
-
Avoid use in complete biliary obstruction
-
Use during pregnancy only if clearly advised by a physician
-
Long-term therapy may be required for chronic conditions
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Drug Interactions
Ursotab Tablet may interact with:
-
Cholestyramine and other bile acid sequestrants (reduce absorption)
-
Aluminum-containing antacids
-
Estrogen-containing oral contraceptives (may reduce effectiveness)
Maintain proper time gaps between medications when co-administered.
Storage
-
Store below 30°C in a dry place
-
Protect from moisture and light
-
Keep out of reach of children.