Canider Tablet contains Lercanidipine Hydrochloride 10 mg, a calcium channel blocker used primarily to treat hypertension (high blood pressure). By relaxing the smooth muscles in blood vessels, Lercanidipine reduces vascular resistance, allowing blood to flow more easily. This action helps lower blood pressure, reducing the risk of complications such as stroke, heart attack, and kidney damage.

Lercanidipine is part of the dihydropyridine class of calcium channel blockers, known for its slow onset and long-lasting effect, making it suitable for once-daily dosing. It provides effective blood pressure control with a low risk of reflex tachycardia and peripheral edema, which are common with some other calcium channel blockers.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Canider Tablet 10 mg is indicated for:

• Essential hypertension: To lower and maintain blood pressure within the normal range
• Prevention of cardiovascular complications: Reduces the risk of stroke, myocardial infarction, and heart failure in hypertensive patients
• Can be used as monotherapy or in combination with other antihypertensive agents for better control

Composition

• Active Ingredient: Lercanidipine Hydrochloride
• Strength: 10 mg per tablet
• Dosage Form: Oral tablet

Mechanism of Action

Lercanidipine is a dihydropyridine calcium channel blocker. Its mechanism involves:

• Blocking calcium entry into vascular smooth muscle cells
• Causing vasodilation of peripheral arteries
• Reducing peripheral vascular resistance, which lowers blood pressure
• Decreasing cardiac workload, improving oxygen supply to the heart

By targeting calcium channels in blood vessels, Lercanidipine provides stable and sustained blood pressure reduction with minimal effects on heart rate.

Dosage & Administration

• Adults: 10 mg once daily, preferably at the same time each day
• Can be taken with or without food, although taking it with food may enhance absorption
• Dose may be adjusted based on response, with a maximum of 20 mg daily if required
• Gradual dose titration may be recommended for patients with liver impairment

Side Effects

Canider Tablet is generally well tolerated. Common side effects may include:

• Headache
• Flushing
• Dizziness or lightheadedness
• Mild swelling of ankles or feet (peripheral edema)
• Rare: palpitations, gastrointestinal disturbances, or allergic reactions

Patients experiencing severe side effects should consult their physician immediately.

Precautions & Warnings

• Use with caution in patients with severe hypotension, liver disease, or heart failure
• Regular blood pressure monitoring is recommended during therapy
• Avoid abrupt discontinuation to prevent rebound hypertension
• Inform your doctor of all concurrent medications to prevent potential drug interactions

Drug Interactions

• May interact with CYP3A4 inhibitors or inducers, other antihypertensives, and grapefruit juice
• Always inform your physician about all medications, supplements, and herbal products being used

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Use only if clearly necessary under medical supervision
• Lactation: Consult a physician before use
• Elderly: Monitor for hypotension and dizziness; dose adjustment may be necessary
• Pediatrics: Safety and efficacy not established

Storage

• Store below 25°C in a cool, dry place
• Protect from light and moisture
• Keep tablets in the original packaging
• Keep out of reach of children.